'All vaccine adjuvants are, by definition, toxic. Their function is to stimulate the immune system, that is, to initiate a response to a toxic agent. So, a new generation of adjuvants is being promoted as less toxic than any that have come before, while at the same time doing an even better job of priming the immune system so it will react to weak antigens.
This leads to the question of how an adjuvant can be both safer than previous adjuvants and also more capable of agitating the stronger immune system response required to promote antibody creation to weaker antigens.
These new adjuvants are made from outer membrane vesicles (OMVs). A vesicle is a cavity, or sac. In a bacterium, OMVs are sacs that protrude from the exterior—membrane—of its body to protect itself in hostile environments. An OMV’s function is to be toxic.'
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